Cannabigerol, a compound commonly called CBG, is among the cannabinoids popularly present in the cannabis plant. Although a minor compound, it can be extremely useful for those who want to witness the health advantages of cannabinoids.
CBG is also a supreme molecule, similar in value as the stem cells are for the human body. They’ve been touted as cancer-healing, youth-conserving, and all-curing cells. Scientists all over the world are attempting to treat all things from weak eyesight to cancer employing stem cells. Likewise, CBG can also aid to treat disorders like:
- Multiple Sclerosis
- Some types of cancer
- Chronic pain
- Inflammatory bowel diseases
- Bladder dysfunctions
Of course, it is also equally helpful in treating spondylitis.
What Is Spondylitis?
Spondylitis impacts the spinal column. It can lead to inflammation and stiffness between your vertebrae – the bones of your spine, neck, and lower back, besides the pelvis. Spondylitis can also invade ligaments that join muscles to bones and different connective tissue.
This ailment is a comparatively unique form of acute progressive arthritis that occasionally contains a genetic component. The most prominent type is ankylosing spondylitis – an inflammatory situation that mainly impacts the joints of the lower back where the spine joins the hips. Ankylosing spondylitis can create symptoms such as back pain and stiffness, apart from causing the spine to slowly lose flexibility with time. In acute cases, this causes an aggravated curvature of the spine.
Currently, no known cure exists for ankylosing spondylitis. Accordingly, the aims of treatment are normally to control pain and inflammation apart from slowing down its progress.
Causes of cervical spondylosis include:
- Bone spurs
- Dehydrated spinal discs
- Herniated discs
- Ligament stiffness
Factors apart from aging your chances of cervical spondylosis include:
- Neck injuries
- Work-based activities that place additional strain on your neck from heavy raising
- Keeping your neck in an uncomfortable position for extended periods of time or performing similar neck
- movements across the day (recurrent stress)
- Genetic factors (family history of cervical spondylosis)
- Being inactive and overweight
CBG Gives You Relief From Spondylitis
The powerful anti-inflammatory effects of CBG can help to relieve pain in spondylitis. Our bodies utilize the endocannabinoid system involved in keeping the body’s homeostasis and perform bodily processes like managing pain, keeping the mood upbeat, regulating temperature, appetite and also sleep, to name a few. At the site of an injury, the endocannabinoid system can serve to control immune cells to restrict inflammation. CBG communicates with the endocannabinoid mechanism through the CB2 receptors to regulate the immune responses and lower pain in spondylitis.
Because it is non-psychotropic, CBG possesses an inspiring wide range of potential applications, not only for the above-mentioned problems but even as an analgesic for relieving pain. CBG is neuroprotective, and so protects and safeguards the nerves of the brain and spinal cord from injury, disease, and degeneration.
CBG can also decrease the production of nitric oxide which is responsible for inflammation. Therefore, it can help in reducing any flare-up resulting from spondylitis.
The pain-relieving properties of CBG are due to the effects which it casts upon individual cells. CBG acts neutrally upon the CB1 receptor, however, it activates the CB2 receptor and restricts the TRPM8 receptor thereby lowering pain. Moreover, CBG constitutes an alpha-2 agonist and binds to the receptor to cause a similar response like adrenaline and noradrenaline. Moreover, CBG is also a 5HT1A antagonist. By activating the alpha-2 receptor and restricting the 5HT1A receptor, a synergistic advantage is imparted by CBG. Pain, which comprises a mix of emotions and physical symptoms is most successfully treated in the event of dual-receptor stimulation, which is witnessed with the activation of the alpha-2 receptor and the inhibition of the 5HT1A receptor.
CBG acts as a preserver of nerves from degeneration. It is effective in spondylitis as it offers neuroprotection in the way similar to other diseases like Alzheimer’s and multiple sclerosis.
Being a muscle-relaxant for spastic conditions CBG can help in stiffness of muscles that sufferers of spondylitis often experience. This analgesic compound has a promising future in relieving pain and offering a panacea for improving bone conditions, stiff neck as well as overall inflammation.