The building block of cannabinoids is CBG or cannabigerol. This cannabinoid comprises the starting spot for CBD, THC, and CBC and constitutes a stimulant for bone growth, brain cells, appetite, besides as a suppressant for cancer cells. CBG is reared from CBG-A (cannabigerolic acid) which is said to be the stem cell of all cannabinoids. In fact, CBG is cannabigerolic acid in its non-acidic form. The medicinal impact that cannabis offers is possible due to CBG-A.
CBG also possesses sedative, anti-seizure, and anti-inflammatory features. Though CBG is not psychoactive in itself, it is found sufficiently inside low-THC but high-CBD strains of the cannabis plant.
What Precisely Is CBG?
CBG (cannabigerol) comprises a non-acidic cannabinoid formed by the application of heat to the CBGA (cannabigerolic acid) molecule. CBC, CBD, and THC constitute it’s near chemical relatives.
CBG occurs mostly in hemp products, and strains reared for high THC normally carry extremely low concentrations of CBG (lower than 1%). Conversely, high CBD strains include much greater concentrations of this vital cannabinoid.
Benefits Of CBG
The benefits of CBG is closely linked to its action in the human body. CBG can function as an:
Antibacterial (retards growth of bacteria)
- Analgesic (alleviates pain)
- Anti-inflammatory (lowers inflammation)
- Anti-convulsive (lessens convulsions and seizures)
- Anti-proliferative (restricts the growth of cancer cell)
- Anti-insomnia (assists sleep)
- Bone stimulant (supports bone growth)
- Antidepressant (elevates mood)
- Appetite stimulant (raises appetite)
- Brain cell stimulant (supports neuron growth)
Due to its benefits, CBG can be used to treat various disorders like Glaucoma, Cancer, Protects neurons in Multiple Sclerosis and Huntington’s, and Inflammatory Bowel Disease such as Crohn’s.
Crohn’s Disease – What It Is?
Crohn’s disease refers to a chronic disease that mainly affects the mucosal coating of the digestive tract of the body. It can extend into deeper layers of the gut tissue. Surprisingly, Crohn’s disease comprises a likely lethal state of the gastrointestinal tract that induces aggravation, nausea, pain and unusual weight loss. In many cases, Crohn’s Disease starts with irritation within the mouth, which shifts below into the stomach, bowel, and anus.
Patients of Crohn’s Disease mostly experience various painful symptoms like chronic stomach pain and cramping, nervousness, aggravation, fever, loose bowels, weight loss, chronic weariness, bloody stools, and occasionally also mouth sores.
Cannabinoids, like CBG, have potential therapeutic utility for different gastrointestinal conditions, like gastric ulcers, IBS, Crohn’s disease, paralytic ileus, secretory diarrhea, and gastroesophageal reflux disease.
CBG For Crohn’s Disease
Inflammatory Bowel Disease (IBD) is a chronic condition which includes Ulcerative Colitis and Crohn’s Disease. CBG has emerged as a potential treatment for IBD. The endocannabinoid system (ECS) is involved in gut hemostasis, visceral sensation, gastrointestinal motility, and inflammation. Research indicates that the modulation of ECS might play a major role in the pathogenesis of IBD, and aid patients handle their symptoms like abdominal and joint pain, diarrhea, cramping, weight loss, bad appetite, and nausea.
Especially, the impact of Cannabigerol (CBG), a non-psychotropic cannabinoid, is beneficiary to aid treat IBD. The effects of CBG within a murine model of colitis was studied and results indicated CBG lowered colon weight to colon length ratio, myeloperoxidase action, and iNOS expression; elevated SOD activity; and standardized interleukin-10, interleukin-1β, and interferon-γ alterations. These SOD (Superoxide Dismutases) consist of antioxidant enzymes that are integral to the defense mechanism of our body. Thus, CBG might be contemplated for clinical experimentation with IBD patients. Furthermore, an observational study has shown CBG to be safe for humans to employ for managing their IBD.
Your ECS (Endocannabinoid system) is a vast network of neurotransmitter that regulates the balance with regard to various bodily systems and performing as an excellent communicator. Its communications are constituted of receptors and chemical messengers. These receptors within our endocannabinoid system traverse all over our body from the brain and nervous mechanism to the immune system and the periphery. CBG can work effectively on both the cannabinoid receptors CB1 plus CB2.
As CB2 receptors are situated densely within the GI system (Gastrointestinal system) they are accountable for moderating inflammatory responses. This is the main reason as to why patients of IBS or Crohn’s benefits from cannabinoid medication like CBG. By directing itself on the molecules that cause inflammation CBG can heal chronic pain, IBD and also the growth of the cancer cell.
CBG is the forgotten hero of our endocannabinoid system. This can be said because various cannabinoids like CBD or THC, start as CBG. The acid version of CBG that is CBG-A or cannabigerolic acid is broken by the natural enzymes of the cannabis into CBDA, THCA as well as CBCA. As the plant gets heated, these acids are modified into the types and forms with which we are more aware like THC, CBD, and CBC. With immense health benefits from presenting positive impact on depression, healing bone fractures to neuropathic pain relief and anti-inflammation CBG can well become a therapeutic compound with huge potential.
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